Glutathione Whitening Treatment, commonly known as IU Injection

What is Glutathione?

Glutathione is an important antioxidant substance widely distributed in various organs of our body, including the liver, kidneys, and brain.

This substance removes active oxygen, alleviating cell damage, and aids the function of other antioxidant components like Vitamins C and E. As a result, it contributes to protecting cells and preventing aging.

Effects of Glutathione on Skin Whitening

Beyond its simple antioxidant function, glutathione can help improve skin tone to be clearer and more even.

Inhibition of Tyrosinase Enzyme Activity

It inhibits the activity of tyrosinase, a key enzyme in melanin production, thereby reducing the excessive creation of pigments.

Regulation of Melanin Production Pathway

Glutathione reduces the synthesis of dark-colored eumelanin and induces the production of lighter-colored pheomelanin, thereby contributing to an overall brighter skin tone.

Alleviation of Pigment Production Through Antioxidant Action

When active oxygen is generated due to UV exposure, heat stimulation, or inflammatory responses, melanin production can be promoted. In such cases, glutathione neutralizes these active oxygen species, playing a role in reducing the fundamental stimuli that trigger pigment production.

Synergistic Effect with Vitamin C

Vitamin C plays a role in restoring oxidized glutathione to its active state. This activated glutathione inhibits melanin production, allowing the two ingredients together to positively influence skin whitening.

Consequently, glutathione helps reduce melanin production and induces lighter pigment pathways, thereby helping the skin tone become naturally brighter and more even.

Glutathione Treatment: What Makes It Special?

You may have encountered glutathione in oral supplements or injection forms. However, these methods each have their limitations.

Limitations of Oral Intake (Ingesting Glutathione)

Orally ingested glutathione has a low absorption rate in the gastrointestinal tract, and most of the absorbed amount is metabolized in the liver. Consequently, the amount that reaches the skin to exert its effects can be very small.

This process is precisely why it's difficult to expect an immediate skin brightening effect.

Considerations for Intravenous Injection Method

Since intravenous injections disperse the ingredients throughout the entire body, it's not easy for them to act intensively on specific areas.

While it can contribute to liver function improvement or systemic antioxidant effects, when targeting facial hyperpigmentation or skin tone improvement, the specificity of ingredient delivery may be insufficient.

Differentiated Glutathione Treatment Method

Iontophoresis Application: Utilizing a special current, glutathione is effectively delivered through the skin barrier, close to the dermis layer. This method can compensate for the limitations of oral intake or intravenous injections.

Targeted Delivery to Necessary Areas: Instead of dispersing throughout the body, the ingredient is specifically absorbed into facial areas requiring pigment improvement and skin tone management.

Use of Undiluted Solution: For maximum efficacy during treatment, we use undiluted glutathione concentrate ampoules. This helps to fully activate glutathione's antioxidant and whitening properties.

This glutathione care is designed based on an approach that is "more direct than oral intake and more localized than injections."

Benefits of Iontophoresis Absorption Method

Limitations of Oral Intake: When glutathione is ingested, its absorption rate through the gastrointestinal tract is inconsistent, and it is difficult for a sufficient amount to reach the skin due to metabolism in the liver.

Limitations of Simple Topical Application: The stratum corneum on the skin's surface is a powerful barrier protecting our body from external substances. Water-soluble ingredients like glutathione find it difficult to penetrate this barrier deeply.

Key Benefits of Iontophoresis:

Electrical Repulsion Effect: Utilizing glutathione's negative charge, a current of the same polarity is used to push the ingredient inward through the skin barrier, aiding penetration.

Electro-Osmosis Effect: Microfluidic flow occurs, expanding the pathways through which active ingredients can be absorbed.

Deep Active Ingredient Delivery: The goal is to effectively deliver active ingredients not just to the skin's surface, but to areas close to the dermis layer.

In summary, iontophoresis is a method that allows active ingredients to be absorbed 'more directly than oral intake, and more deeply than simple topical application'.

Glutathione Treatment Cycle and Recommended Frequency

Treatment Cycle: It is recommended to proceed at 1-week intervals.

Recommended Sessions: For optimal results, it may be beneficial to consistently receive at least 5 sessions.

Maintenance Care: Even after the treatment is completed, regular follow-up care can help maintain the improved skin tone stably.